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Healthy Aging

The 2 primary functions of this pathway are (1) the generation of NADPH for use in other reductive biosynthetic (anabolic) pathways and (2) to convert glucose carbons into ribose 5-phosphate (R5P) for the synthesis of the nucleotides and nucleic acids

Prescribers should still exercise caution with any GH-axis stimulation in patients with liver disease, given GH's effects on hepatic glucose metabolism and IGF-1 production